Key result
Implantation of the Freedom Solo stentless aortic valve yielded favourable transvalvular gradients (mean 8.6 mmHg at 4.2 months) but 76% of patients developed postoperative thrombocytopenia.
Why the study?
What is the haemodynamic performance and effect on thrombocyte levels of the Freedom Solo stentless aortic valve?
Observational (n=37)
No
What is the haemodynamic performance and effect on thrombocyte levels of the Freedom Solo stentless aortic valve?
The Freedom Solo stentless aortic valve demonstrates favorable early hemodynamics but is associated with a high rate of postoperative thrombocytopenia.
Thrombocytopenia risk with Freedom Solo valve merits monitoring; case report leaves open questions on causality and clinical impact.
OBJECTIVES: Freedom Solo is a stentless biological aortic valve which is implanted supra-annularly with a single suture line. An increased risk of postoperative thrombocytopenia in the early postoperative period has been reported in recent studies. In our study we evaluated postoperative haemodynamic performance and thrombocyte-levels. DESIGN: Thirty seven patients who underwent valve implantation of the Sorin Freedom Solo stentless valve were included. The haemodynamic performance of the valve was evaluated by transthoracic echocardiography postoperatively at the fourth day (mean) and after a median of 4.2 months. RESULTS: The mean gradient (mmHg) of Freedom Solo was 7.5 at four days and 8.6 at 4.2 months. Postoperatively no patient had more than grade 1 leakage. Seven percent of the patients had a reduction of thrombocytes to less than 20% of the preoperative level. Seventy six percent had a minimum postoperative thrombocyte level less than 100*10(9)/L. The 30 days mortality in our patient material was zero. CONCLUSIONS: Implantation of the Freedom Solo valve was uncomplicated in our experience. Favourable transvalvular gradients and no significant leaks were found. In accordance with the literature, we found a high percentage of patients having a postoperative level of thrombocytes less than 100*10(9)/L after implantation of Freedom Solo.
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Kolseth et al. (2010) conducted an observational in Aortic valve disease (n=37). Sorin Freedom Solo stentless aortic valve was evaluated on Postoperative haemodynamic performance and thrombocyte-levels. Implantation of the Freedom Solo stentless aortic valve yielded favourable transvalvular gradients (mean 8.6 mmHg at 4.2 months) but 76% of patients developed postoperative thrombocytopenia.
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