Why the study?
Do heart rate variability parameters indicate an increased risk of arrhythmia in patients with frequent ventricular ectopic beats without structural heart disease?
Population
86 patients without cardiovascular disease
Comparison
24-hour ECG recording for heart rate variability… vs 43 control patients without frequent ventricular…
Design
Case-control
Key result
Frequent ventricular ectopic beats were associated with a significantly higher LF/HF ratio (P<0.001) and a higher rate of paroxysmal atrial fibrillation (P=0.003) compared to controls.
Authors
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Frequent VEBs link to sympathetic HRV dominance and higher paroxysmal AF; leaves open whether HRV aids risk stratification in observational cohorts.
Case-Control (n=86)
Do heart rate variability parameters indicate an increased risk of arrhythmia in patients with frequent ventricular ectopic beats without structural heart disease?
p-value: p=<0.001
Patients with frequent ventricular ectopic beats without structural heart disease exhibit sympathetic nervous system dominance and have a higher risk of paroxysmal atrial fibrillation.
Barutçu et al. (2014) conducted a case-control in Frequent ventricular ectopic beats without structural heart disease (n=86). Frequent ventricular ectopic beats vs. Controls was evaluated on LF/HF ratio and rate of paroxysmal atrial fibrillation (PAF) (p=<0.001). Frequent ventricular ectopic beats were associated with a significantly higher LF/HF ratio (P<0.001) and a higher rate of paroxysmal atrial fibrillation (P=0.003) compared to controls.