Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 2014FEBS Open BioOpen Access

Mycobacterium tuberculosis PE25/PPE41 protein complex induces necrosis in macrophages: Role in virulence and disease reactivation?

View Full Paper
Ask AI
Bookmark
Share

Authors

STSmanla TundupKMKrishnaveni MohareerSHSeyed E. Hasnain

Discussion

Loading...

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Tundup et al. (2014) studied this question.

synapsesocial.com/papers/6aa677efbc2c7db7488e6376https://doi.org/10.1016/j.fob.2014.09.001
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Human Macrophages Infected with a High Burden of ESAT-6-Expressing M. tuberculosis Undergo Caspase-1- and Cathepsin B-Independent Necrosis2011 · 130 citations
  2. 2Survival of <i>Mycobacterium tuberculosis</i> in Host Macrophages Involves Resistance to Apoptosis Dependent upon Induction of Antiapoptotic Bcl-2 Family Member Mcl-12003 · 245 citations
  3. 3Evidence that Mycobacterial PE_PGRS Proteins Are Cell Surface Constituents That Influence Interactions with Other Cells2001 · 274 citations
  4. 4Execution of Macrophage Apoptosis by PE_PGRS33 of Mycobacterium tuberculosis Is Mediated by Toll-like Receptor 2-dependent Release of Tumor Necrosis Factor-α2006 · 208 citations
  5. 5Mycobacterial Secretion Systems ESX-1 and ESX-5 Play Distinct Roles in Host Cell Death and Inflammasome Activation2011 · 153 citations