Key result
Epidural 30-mL saline washout accelerates full motor recovery by ~26 minutes vs. 1-mL control.
Why the study?
The effectiveness of an epidural normal saline bolus on motor and sensory block recovery and hemodynamic stability in non-obstetrical patients receiving 0.5% bupivacaine had not been investigated.
Does an epidural bolus of 30-mL normal saline reduce the time to full motor recovery in non-obstetrical patients undergoing 0.5% bupivacaine epidural anesthesia?
RCT (n=22)
Double-blind
Table of random numbers
No
Does an epidural bolus of 30-mL normal saline reduce the time to full motor recovery in non-obstetrical patients undergoing 0.5% bupivacaine epidural anesthesia?
A 30-mL epidural normal saline washout significantly accelerates motor recovery following 0.5% bupivacaine epidural anesthesia without compromising hemodynamic stability.
May enable earlier ambulation after bupivacaine epidural; confirms efficacy of saline washout in an RCT.
Background: Prolonged motor and sensory block following epidural anesthesia has been associated with patient dissatisfaction. Administration of epidural crystalloids in patient who had received bupivacaine 0.75% and lidocaine 2% epidural anesthesia. However, bupivacaine 0.5% is commonly used in our institutional and the effectiveness of bolus of NS in non-obstetrical patients undergoing 0.5% bupivacaine epidural anesthesia has not been investigated. The objective of this study was to determine the relationship of normal saline (NS) epidural flush volume to the recovery of motor and sensory block and its hemodynamic stability (blood pressure and heart rate) in non-obstetrical patients undergoing epidural anesthesia using 0.5% bupivacaine. Methods: Following surgery, subjects with T6 dermatome level of sensory, were randomized to 2 treatment groups. Group 1 (control, n = 11) received 1-mL epidural normal saline (NS). Group 2 (experimental, n = 11) received an epidural bolus of 30-mL NS. Assesment of motor and sensory block was performed at 15-minute intervals until complete motor and sensory recovery. Hemodynamic stability (blood pressure and heart rate) between two groups were also monitor every 15-minutes and determined. Results: Times to full motor recovery were significantly faster in the epidural bolus of 30-mL groups than in the control group (69 ± 19.66 vs 95 ± 11.83; p = 0.0017).). Conclusions: A more rapid recovery of motor block in patients undergoing 0.5% bupivacaine epidural anesthesia can be achieved with the use of 30-mL NS epidural washout, with hemodynamic stability.
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Sinatra et al. (2021) conducted an RCT in Epidural anesthesia for elective gynecologic procedures (n=22). Epidural normal saline washout vs. 1 mL epidural normal saline was evaluated on Time to complete motor recovery (minutes) (26 minutes faster, p=0.0017). A 30-mL epidural normal saline washout significantly accelerated full motor recovery by 26 minutes compared to a 1-mL control in patients undergoing 0.5% bupivacaine epidural anesthesia.
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