Synthesis and reactions of 3-aminotetrachloroquinazolin-2,4-dione

This is the authors' abstract. We don't add key points for this paper.

N -phenylsulphonyloxytetrachlorophthalimide was obtained by treatment of N -hydroxy tetrachlorophthalimide with benzenesulphonyl chloride. Also, the titled compound 3 was obtained by reaction of compound 2 with hydrazine hydrate via Lossen rearrangement. Compound 3 used as starting material for the synthesis of new pyrimidine and quinazolinedione derivatives containing four chlorine atoms which have pharmacological activity.