Key result
Early AVSD repair at 2 to 4 months proves safe without increasing postoperative regurgitation risk.
Why the study?
Does surgical repair in early infancy improve outcomes in infants with atrioventricular septal defect with a common atrioventricular valve?
Does surgical repair in early infancy improve outcomes in infants with atrioventricular septal defect with a common atrioventricular valve?
Early surgical repair of atrioventricular septal defect at 2 to 4 months of age is safe and mitigates pulmonary hypertension crises without increasing postoperative valve regurgitation risk.
May support earlier repair to mitigate pulmonary hypertension crises in atrioventricular septal defect; leaves open optimal timing pending prospective trials.
The repair of atrioventricular septal defect with a common atrioventricular valve is reconstructive surgery at its best, and hence one of the favourite operations performed by paediatric cardiac surgeons. In the past, the post-operative course from such patients was dominated by the occurrence of pulmonary hypertension crises, which were responsible for significant morbidity and mortality. Nowadays, repair is generally undertaken early in infancy, and this approach has mitigated the problems emanating from pulmonary hypertension. Coupled with a better understanding of the anatomy, and adaptation of the surgical techniques, repair can now be achieved safely at around 2 to 4 months of life, without increasing the risk of postoperative regurgitation across the reconstructed left atrioventricular valve. In this review, we discuss the surgical techniques required for, and clinical results of, such early repair.
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Lacour-Gayet et al. (2006) conducted a review in Atrioventricular septal defect with common atrioventricular valve. Surgical repair in early infancy was evaluated. Surgical repair of atrioventricular septal defect with a common atrioventricular valve can be achieved safely at 2 to 4 months of life without increasing the risk of postoperative regurgitation.
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