What is the clinical evidence from this study?

Study design: Case Report. Population: Idiopathic purulent pericarditis (n=1). Intervention: Pericardiocentesis, mediastinal washout, and intravenous cefazolin. Primary outcome: Clinical recovery.

What does this research mean for the field?

Idiopathic purulent pericarditis caused by methicillin-sensitive Staphylococcus aureus can occur in immunocompetent adults and be successfully managed with pericardiocentesis, serial pericardial washouts, and prolonged intravenous antibiotics. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To describe a rare presentation of idiopathic acute purulent pericarditis complicated by cardiac tamponade in an immunocompetent individual.

March 29, 2021CureusOpen Access

Idiopathic Purulent Pericarditis Caused by Methicillin-Sensitive Staphylococcus Aureus in an Immunocompetent Adult

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Key result

Pericardiocentesis, multiple washouts, and IV antibiotics successfully resolve idiopathic MSSA purulent pericarditis.

Why the study?

Acute purulent pericarditis is exceedingly rare and carries near 100% mortality untreated, prompting the report of an idiopathic case caused by methicillin-sensitive Staphylococcus aureus.

Population

One 69-year-old male with pericardial effusion and tamponade

Design

Case report

Authors

DHDeanna L Huffman MSMina ShnodaSouthern Illinois University School of Medicine KSKarthik ShankarLankenau Medical Center

Discussion

Member takes

Implication

Supports early drainage and antibiotics in suspected purulent pericarditis; single case leaves optimal regimen and generalizability open.

Key Points

To describe a rare presentation of idiopathic acute purulent pericarditis complicated by cardiac tamponade in an immunocompetent individual.
Clinical presentation and management of a 69-year-old immunocompetent male presenting with chest and abdominal pain (N=1).
Interventions included emergent pericardiocentesis, microbial culture analysis, repeated pericardial washouts, and four weeks of targeted intravenous antibiotic therapy.
Pericardial fluid cultures isolated methicillin-sensitive Staphylococcus aureus without an identifiable primary source of infection.
The patient successfully recovered following multiple pericardial washouts and a completed four-week course of intravenous antibiotics.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 69-year-old immunocompetent male who presented with chest and abdominal pain and was diagnosed with idiopathic purulent pericarditis caused by methicillin-sensitive Staphylococcus aureus.

Intervention

Emergent pericardiocentesis, multiple pericardial washouts, and 4 weeks of intravenous antibiotics

Highlights a rare case of idiopathic purulent pericarditis caused by MSSA in an immunocompetent adult, emphasizing the need for high clinical suspicion and prompt treatment.

Cite This Study

Huffman et al. (2021) conducted a case report in Idiopathic purulent pericarditis (n=1). Pericardiocentesis, mediastinal washout, and intravenous cefazolin was evaluated on Clinical recovery. A 69-year-old immunocompetent male with idiopathic purulent pericarditis caused by methicillin-sensitive Staphylococcus aureus was successfully treated with pericardiocentesis, multiple washouts, and intravenous antibiotics.

synapsesocial.com/papers/6aa68bdbd3d41ccc68923550 https://doi.org/10.7759/cureus.14173

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Idiopathic Purulent Pericarditis Caused by Methicillin-Sensitive Staphylococcus Aureus in an Immunocompetent Adult

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Idiopathic Purulent Pericarditis Caused by Methicillin-Sensitive Staphylococcus Aureus in an Immunocompetent Adult

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider