Key result
Severe mental disorders are linked to ~2x higher prevalence of major CV risk factors.
Why the study?
Is the prevalence of cardiovascular risk factors higher in patients with severe mental disorders compared to the general population?
Cross-Sectional (n=18,975)
Is the prevalence of cardiovascular risk factors higher in patients with severe mental disorders compared to the general population?
Patients with severe mental disorders, particularly younger individuals, have a significantly higher burden of cardiovascular risk factors that cannot be explained by sociodemographic variables alone.
Supports enhanced cardiovascular risk screening in severe mental disorders; cross-sectional data leaves open causal mechanisms and intervention effects.
OBJECTIVE: To study the prevalence and distribution of cardiovascular risk factors in a group of patients with severe mental disorders compared with the general population and investigate if differences in sociodemographic background variables between groups were associated with differences in risk profile. METHOD: We compared data from the ongoing Ulleval 600 Study (205 pharmacologically stable outpatients with DSM-IV psychotic disorders) with data from the 2000-2001 Oslo Health Study (18,770 individuals from the general population of the same area). Subjects were stratified according to age and gender and compared for ethnic background, level of education, marital status, and prevalence of risk factors. RESULTS: Patients had an overall prevalence of smoking, obesity, hypertension, dyslipidemia, and diabetes mellitus about twice that of the reference group. Patients aged 18 through 50 years had the highest level of risk factors when compared with the general population. There was no major difference in ethnic background or educational level between cohorts. CONCLUSION: The increased cardiovascular risk profile in patients is particularly pronounced in young individuals and could not be explained by sociodemographic variables alone.
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Birkenaes et al. (2006) conducted a cross-sectional in Severe mental disorders (n=18,975). Severe mental disorders (psychotic disorders) vs. General population was evaluated on Prevalence of cardiovascular risk factors (smoking, obesity, hypertension, dyslipidemia, and diabetes mellitus). Severe mental disorders were associated with about twice the prevalence of smoking, obesity, hypertension, dyslipidemia, and diabetes mellitus compared with the general population.
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