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January 1, 2014Chemical Science

Total synthesis and characterization of thielocin B1 as a protein–protein interaction inhibitor of PAC3 homodimer

Takayuki Doi Masahito Yoshida Kosuke Ohsawa Kazuo Shin‐ya Motoki Takagi Yoshinori Uekusa Takumi Yamaguchi Koichi Kato Takatsugu Hirokawa Tohru Natsume

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Abstract

We have characterized the inhibition of the protein–protein interaction of the homodimer of proteasome assembling chaperone (PAC) 3 with thielocin B1.

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Doi et al. (2014) studied this question.

synapsesocial.com/papers/6aa69b9f246eab12a27f556e https://doi.org/10.1039/c3sc53237b

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