Key result
Rare large-cell calcifying Sertoli cell tumor is linked to cardiac myxoma and endocrine disorders.
Case Report (n=1)
Clinicians should be aware of large-cell calcifying Sertoli cell tumors due to their association with endocrine abnormalities and cardiac myxomas.
Case awareness of large-cell calcifying Sertoli cell tumors may prompt cardiac myxoma evaluation; leaves open prospective studies on screening utility.
We report on a 20-year-old man with a left testicular mass clinically believed to be a malignant neoplasm but subsequently identified as a large-cell calcifying Sertoli cell tumor. This is a rare form of Sertoli cell tumor with unique clinical and pathological features only recently described in the literature. The neoplasm has a low malignant potential with only 1 patient known to have had metastasis. The tumor occurs primarily during the first 2 decades of life and has been associated with endocrine disorders and cardiac myxoma. The clinician should be mindful of this tumor because of its low malignant potential and the necessity to evaluate individuals for endocrine and cardiac abnormalities.
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Buchino et al. (1989) conducted a case report in Large-cell calcifying Sertoli cell tumor (n=1). A 20-year-old man was diagnosed with a rare large-cell calcifying Sertoli cell tumor, a neoplasm with low malignant potential that is associated with endocrine disorders and cardiac myxoma.
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