What does this research mean for the field?

Contractile differentiation in foetal cattle muscles proceeds through at least two generations of cells, with differentiation precocity and fiber-type destiny being muscle-specific and linked to postnatal function. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 1999annales de biologie animale biochimie biophysiqueOpen Access

Contractile differentiation of foetal cattle muscles: intermuscular variability

Q: What is the clinical evidence from this study?

Study design: Other. Population: Foetal muscle development (n=31). Intervention: Muscle type (Masseter, Diaphragma, Biceps femoris, Longissimus thoracis, Semitendinosus, Cutaneus trunci). Primary outcome: Contractile differentiation and myosin heavy chain expression.

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Key result

Foetal cattle muscle differentiation involves at least two cell generations linked to birth function.

n=31

Authors

HGHélène Gagnière BPBrigitte PicardUniversité Clermont Auvergne YGY. GeayCenter for Economic and Policy Research

Discussion

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Implication

Hypothesis-generating in bovine myogenesis; leaves open parallels for human cardiac muscle development.

PICO

Population

31 Charolais cattle foetuses aged 60 to 260 days were studied to evaluate the contractile differentiation of six different skeletal muscles.

Exposure / Comparator

Muscle type (Masseter, Diaphragma, Biceps femoris, Longissimus thoracis, Semitendinosus, Cutaneus trunci)

Primary Outcome

Contractile differentiation and myosin heavy chain expression

Limitations

The existence of a third generation of cells and its origin needs to be confirmed.

Cite This Study

Gagnière et al. (1999) studied Foetal muscle development (n=31). Muscle type (Masseter, Diaphragma, Biceps femoris, Longissimus thoracis, Semitendinosus, Cutaneus trunci) was evaluated on Contractile differentiation and myosin heavy chain expression. Contractile differentiation in foetal cattle muscles involves at least two generations of cells, with the precocity of differentiation being muscle-type dependent and related to muscle function at birth.

synapsesocial.com/papers/6aa69f8922b054842339745d https://doi.org/10.1051/rnd:19990510

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Contractile differentiation of foetal cattle muscles: intermuscular variability

Discussion

Member takes

Implication

PICO

Limitations

Cite This Study

Contractile differentiation of foetal cattle muscles: intermuscular variability

Discussion

Member takes

Implication

PICO

Limitations

Cite This Study

Also Consider

Also Consider