Concomitant Carotid, Mesenteric and Renal Artery Stenosis due to Primary Intimal Fibroplasia

We report 2 cases of primary intimal fibroplasia involving the carotid, mesenteric and renal arteries. These patients presented with hypertension and neurological symptoms. Clinical and histologic features of neurofibromatosis or Takayasu's arteritis were absent. In both cases successful staged carotid and renovascular reconstruction was performed. Primary intimal fibroplasia may be a more generalized process than has been considered previously.