Key result
Severely obese individuals have a three to five times higher risk of developing heart failure compared to those with normal body weight, yet do not exhibit an increased mortality risk.
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This commentary proposes that the obesity paradox in heart failure could be partially explained by adipose tissue sequestering lipophilic environmental pollutants, preventing their toxic effects on mitochondria.
Duk‐Hee Lee (2024) conducted an editorial in Heart failure. Obesity vs. Normal body weight was evaluated. Severely obese individuals have a three to five times higher risk of developing heart failure compared to those with normal body weight, yet do not exhibit an increased mortality risk.
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