Devastating Worsening Renal Function Following the Initiation of Sacubitril/Valsartan: Falling Between Two Stools

Figures

• 

  Figure 1. Chest X-ray on hospital admission in case 1. A localized infiltration (red arrows) was noted in the left upper lobe.

• 

  Figure 2. Clinical course and medical treatment given in case 1. SBP: systolic blood pressure, eGFR: estimated glomerular filtration rate An illustration of the medical machinery next to the seated person indicates hemodialysis.

• 

  Figure 3. Chest X-ray on hospital admission in case 2. A typical butterfly shadow is noted (red arrows).

• 

  Figure 4. Echocardiogram on hospital admission in case 2. The left and right panels indicate diastolic and systolic phases of parasternal long-axis views, respectively. Preserved left ventricular ejection fraction of 59% and concentric left ventricular hypertrophy with interventricular septum thickness of 13 mm (red arrows) were noted.

• 

  Figure 5. Clinical course and medical treatment given in case 2. SBP: systolic blood pressure, eGFR: estimated glomerular filtration rate