Key result
Adenovirus-36 infection is strongly linked to obesity in preclinical studies.
Highlights the potential role of adenovirus-36 infection in the etiology of obesity, suggesting the need for large-scale epidemiological studies.
Hypothesis-generating for infectious contribution to obesity; does not alter practice and requires prospective multi-ethnic validation.
Obesity, which causes some cancer types and other diseases, is not only a global public health problem, but also a factor that affects country's economy. Endocrinal, environmental, neuronal and genetic factors have important roles on the etiology of obesity. When the possibility that SMAM‐1 animal virus could have a relationship with obesity was observed, obesity studies focused on human adenoviruses. Adenovirus‐36 was first isolated in 1978 and was the first human adenovirus to be tested in terms of infectobesity. Both in vivo and in vitro studies proved the strong relationship between adenovirus‐36 presence and obesity. Therefore, a large-scale study incorporating various ethnicities and age groups is required to investigate the worldwide epidemic of obesity and its links with viruses.
No takes yet. Share an insight, caveat, or question.
Karameşe et al. (2016) conducted a review in Obesity. Adenovirus-36 infection was evaluated. Adenovirus-36 infection is strongly associated with obesity based on in vivo and in vitro studies, necessitating large-scale studies across various ethnicities and age groups.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: