Key result
Structured exercise fails to reduce asymptomatic aortic aneurysm expansion rates compared to no exercise.
Why the study?
To compare the effectiveness and safety of exercise versus no exercise for patients with asymptomatic aortic aneurysm.
Does structured exercise reduce aneurysm expansion or perioperative complications in patients with asymptomatic aortic aneurysm?
Meta-Analysis (n=387)
Does structured exercise reduce aneurysm expansion or perioperative complications in patients with asymptomatic aortic aneurysm?
Structured exercise does not reduce asymptomatic aortic aneurysm expansion but appears safe and may reduce perioperative complications and hospital stay.
Answers are grounded in this paper and cite their sources.
Structured exercise does not reduce aneurysm expansion; confirms safety and suggests perioperative benefits in asymptomatic aortic aneurysm.
We conducted a systematic review to compare the effectiveness and safety of exercise versus no exercise for patients with asymptomatic aortic aneurysm. We followed the guidelines set out in the Cochrane systematic review handbook. We searched Medline, Embase, CENTRAL, LILACS, PeDRO, CINAHL, clinicaltrials.gov, ICTRP, and OpenGrey using the MeSH terms "aortic aneurysm" and "exercise". 1189 references were identified. Five clinical trials were included. No exercise-related deaths or aortic ruptures occurred in these trials. Exercise did not reduce the aneurysm expansion rate at 12 weeks to 12 months (mean difference [MD], -0.05; 95% confidence interval [CI], -0.13 to 0.03). Six weeks of preoperative exercise reduced severe renal and cardiac complications (risk ratio, 0.54; 95% CI, 0.31-0.93) and the length of intensive care unit stay (MD, -1.00; 95% CI, -1.26 to -0.74). Preoperative and postoperative forward walking reduced the length of hospital stay (MD, -0.69; 95% CI, -1.24 to -0.14). The evidence was graded as 'very low' level.
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Oliveira et al. (2020) conducted a meta-analysis in Asymptomatic aortic aneurysm (n=387). Structured exercise vs. No exercise was evaluated on Aneurysm expansion rate (MD -0.05, 95% CI -0.13 to 0.03). Structured exercise did not significantly reduce the aneurysm expansion rate at 12 weeks to 12 months compared to no exercise in patients with asymptomatic aortic aneurysms.
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