Key result
Detecting preclinical atherosclerosis helps identify high CAD risk in asymptomatic hypertensive patients.
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Detection of early atherosclerosis through noninvasive measures of arterial calcification, thickening, and stiffening may improve risk stratification and clinical management in hypertensive patients.
The detection of preclinical atherosclerosis may contribute to better identifying hypertensive subjects at high risk of complications. Three alterations can be diagnosed noninvasively: calcification, thickening, and stiffening of the arterial wall. Their prevalence is increased in asymptomatic hypertensives and their presence may have important prognostic significance, especially with respect to coronary artery disease. They are also ideal targets to test the efficacy of hypertensive therapy on the arterial wall. Finally, the detection of early atherosclerosis may help to improve the clinical management of hypertensive patients.
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Simon et al. (1998) conducted a review in Hypertension. Detection of preclinical atherosclerosis was evaluated. Detection of preclinical atherosclerosis, including arterial calcification, thickening, and stiffening, may help identify asymptomatic hypertensive patients at high risk for coronary artery disease.
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