Key result
3D mapping reveals flat pentameric structures in circoviruses versus trumpet-shaped units in chicken anemia virus.
The structures of circoviruses in the same genus are related, whereas those in different genera are structurally unrelated.
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Genus-specific capsid architectures distinguish circoviruses; extends taxonomy but leaves open links to host range or intervention.
Crowther et al. (2003) studied Circovirus infection. Structural analysis using electron microscopy was evaluated on Viral capsid structure. Three-dimensional maps showed that porcine circovirus type 2 and beak and feather disease virus have similar flat pentameric structures, whereas chicken anemia virus has protruding trumpet-shaped units.
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