Key result
Antidepressants are linked to an increased risk of adverse cardiovascular changes.
Why the study?
Do antidepressant drugs increase the risk of adverse cardiovascular events in patients with depression?
Do antidepressant drugs increase the risk of adverse cardiovascular events in patients with depression?
Antidepressant medications may increase the risk of adverse cardiovascular effects, highlighting the need for cardiovascular monitoring in treated patients.
Answers are grounded in this paper and cite their sources.
May warrant CV monitoring in antidepressant users; leaves open causality pending prospective trials.
Depression is becoming a more and more frequent problem in highly – developed countries. There exist many factors predisposing to the occurrence of the disease. To most commonly mentioned, are organic CNS damage, genetic factors, disorders in neurotransmitters, and hormone dysfunctions. The disease disturbs the functioning of many organs and systems, causing the increase in the risk of the progression of the coronary disease and venous thrombotic- embolic illness. Antidepressants constitute the heterogenic group in terms of their chemical structure and mechanisms of action. Today it is known that applying them indeed increases the risk of the development of disadvantageous changes in the cardio-vascular system. In this study, an attempt of synthetic analysis of the influence of medicines applied in the treatment of depression on cardiovascular diseases was undertaken.
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Opielak et al. (2013) conducted a review in Depression and cardiovascular diseases. Antidepressant drugs was evaluated on Cardiovascular system changes. Antidepressant drugs increase the risk of developing disadvantageous changes in the cardiovascular system.
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