What is the clinical evidence from this study?

Study design: Other. Population: stage 1-3 hypertension (n=667). Intervention: Quinapril. Primary outcome: Blood pressure normalization (SBP < 140 mm Hg and DBP < 90 mm Hg).

What does this research mean for the field?

Physician digit preference in blood pressure measurement significantly alters apparent antihypertensive drug efficacy when normalization thresholds are defined as strictly less than rather than less than or equal to standard cutoffs. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 1, 1997American Journal of Therapeutics

Digit Preferences Observed in the Measurement of Blood Pressure

Q: What are the key findings of this study?

Physician digit preference in blood pressure measurement resulted in apparent quinapril efficacy increasing from 75.1% to 90.7% when normalization criteria were changed from <140/90 to ≤140/90 mm Hg.

Q: What does this research mean for the field?

Physician digit preference in blood pressure measurement significantly alters apparent antihypertensive drug efficacy when normalization thresholds are defined as strictly less than rather than less than or equal to standard cutoffs. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

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Key result

Physician digit preference inflates apparent quinapril efficacy by ~16% when BP targets shift to ≤140/90.

n=667

Why the study?

Does digit preference in blood pressure measurement affect the apparent efficacy of antihypertensive treatment?

Population

667 adult patients 19-83 years of age with stage 1-3 hypertension, treated by 85 physicians in primary…

Design

Cohort, open

Follow-up

12 weeks

Authors

LALuis AlcocerMexican Social Security Institute GNGermán NovoaInstituto de Investigación Biomédica de Salamanca DSDavid SotresIowa State University

Discussion

Member takes

Implication

May bias apparent antihypertensive efficacy estimates; hypothesis-generating for standardized BP protocols in research.

Structured PICO

Does digit preference in blood pressure measurement affect the apparent efficacy of antihypertensive treatment?

Population

667 adult patients aged 19-83 years with stage 1-3 hypertension treated with quinapril for 12 weeks in primary health care.

Intervention

Quinapril for 12 weeks.

Outcome

Digit preference in blood pressure recording and its impact on apparent drug efficacy (normalization defined as SBP < 140 mm Hg and DBP < 90 mm Hg).surrogate

Physicians demonstrate a strong digit preference for multiples of 5 and 10 when recording blood pressure, which can significantly alter the perceived efficacy of antihypertensive treatments depending on the exact cutoff criteria used.

Cite This Study

Alcocer et al. (1997) studied stage 1-3 hypertension (n=667). Quinapril was evaluated on Blood pressure normalization (SBP < 140 mm Hg and DBP < 90 mm Hg). Physician digit preference in blood pressure measurement resulted in apparent quinapril efficacy increasing from 75.1% to 90.7% when normalization criteria were changed from <140/90 to ≤140/90 mm Hg.

synapsesocial.com/papers/6aa6ca22b3a9aaf5308e4cac https://doi.org/10.1097/00045391-199709000-00005

Topics

Hypertension management

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September 1, 1997American Journal of Therapeutics

Digit Preferences Observed in the Measurement of Blood Pressure

View Full Paper

Ask AI

Bookmark

Key result

Physician digit preference inflates apparent quinapril efficacy by ~16% when BP targets shift to ≤140/90.

n=667

Why the study?

Does digit preference in blood pressure measurement affect the apparent efficacy of antihypertensive treatment?

Population

667 adult patients 19-83 years of age with stage 1-3 hypertension, treated by 85 physicians in primary…

Design

Cohort, open

Follow-up

12 weeks

Authors

LALuis AlcocerMexican Social Security Institute GNGermán NovoaInstituto de Investigación Biomédica de Salamanca DSDavid SotresIowa State University

Discussion

Member takes

Implication

May bias apparent antihypertensive efficacy estimates; hypothesis-generating for standardized BP protocols in research.

Structured PICO

Does digit preference in blood pressure measurement affect the apparent efficacy of antihypertensive treatment?

Population

667 adult patients aged 19-83 years with stage 1-3 hypertension treated with quinapril for 12 weeks in primary health care.

Intervention

Quinapril for 12 weeks.

Outcome

Digit preference in blood pressure recording and its impact on apparent drug efficacy (normalization defined as SBP < 140 mm Hg and DBP < 90 mm Hg).surrogate

Cite This Study

synapsesocial.com/papers/6aa6ca22b3a9aaf5308e4cac https://doi.org/10.1097/00045391-199709000-00005

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Topics

Hypertension management

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