Key result
Adding Tongxinluo and danshen to conventional therapy reduces 6-month restenosis by ~59%.
Why the study?
Does the addition of tongxinluo capsule and complex dripping-pill danshen to conventional treatment reduce restenosis in patients post-PCI?
RCT (n=72)
randomly divided
Does the addition of tongxinluo capsule and complex dripping-pill danshen to conventional treatment reduce restenosis in patients post-PCI?
The addition of traditional Chinese medicines (tongxinluo capsule and complex dripping-pill danshen) to conventional therapy significantly reduced angiographic restenosis at 6 months post-PCI.
Answers are grounded in this paper and cite their sources.
Supports adjunctive TCM use post-PCI; extends randomized evidence for restenosis prevention.
Objective To explore the effect of preventing post-PCI restenosis with tongxinluo capsule and complex dripping-pill danshen.Methods Seventy-two patients,accepted percutaneous coronary intervention,were randomly divided into two groups.One received conventional treatment including thirty-six cases(group A),the other received conventional medicine plus tongxinluo capsules and complex dripping-pill danshen including thirty-six cases(group B).Changes of hemorrheology and blood lipid were recorded and the rate of restenosis were counted by coronary artery opacification before and after 6 months treatment in all patients.Results There was different significance between pre-treatment and post-treatment in all observation targets of hemorrheology and blood lipid(P＜0.05).The levels of blood viscosity,plasma viscosity,platelet aggregation,TC,TG and LDL-C were distinctly decreased on the group plus tongxinluo capsules and complex dripping-pill danshen comparaing between two groups post-treatment.And there were different significance between the group B(15.1%)and the group A(37.1%)in the rate of restenosis by coronary artery opacification after 6 months treatment(P＜0.05).Conclusion Tongxinluo capsule and complex dripping-pill danshen can be used as general drugs in preventing restenosis after post-PCI of coronary heart disease patients.
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Yun et al. (2008) conducted an RCT in post-PCI restenosis (n=72). Tongxinluo capsule and complex dripping-pill danshen vs. Conventional treatment was evaluated on rate of restenosis by coronary artery opacification (p=<0.05). Tongxinluo capsule and complex dripping-pill danshen added to conventional treatment reduced the 6-month restenosis rate compared to conventional treatment alone.
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