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March 5, 2008BJU International

The effect of surgical volume, age and comorbidities on 30‐day mortality after radical prostatectomy: a population‐based analysis of 9208 consecutive cases

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Key result

Higher radical prostatectomy volume is linked to ~88% lower 30-day mortality.

  • P=0.049
  • n=9,208

Why the study?

Does surgical volume, age, and comorbidity affect 30-day mortality after radical prostatectomy?

Population

9,208 consecutive patients treated with radical prostatectomy between 1989 and 2000

Design

Cohort

Follow-up

30 days

Authors

JWJochen WalzJohannes Gutenberg University MainzFMFrancesco MontorsiRutgers, The State University of New JerseyCJClaudio JeldresUniversité de Sherbrooke

Discussion

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Implication

Higher SV (>27 cases), younger age and low comorbidity were associated with lower 30-day mortality; leaves open optimal thresholds for referral or selection.

Study Design

Type

Observational (n=9,208)

Structured PICO

Does surgical volume, age, and comorbidity affect 30-day mortality after radical prostatectomy?

P
Population
9,208 consecutive men treated with radical prostatectomy between 1989 and 2000, evaluated for 30-day mortality.
E
Exposure
Radical prostatectomy (assessing the effect of surgical volume, age, and comorbidities)
O
Outcome
30-day mortalityhard clinical

Main Result

Absolute Event Rate: 0.07% vs 0.6%

p-value: p=0.049

Higher surgical volume, younger age, and fewer comorbidities independently predict lower 30-day mortality after radical prostatectomy.

Cite This Study

Walz et al. (2008) conducted an observational in Prostate cancer undergoing radical prostatectomy (n=9,208). Higher surgical volume (>27 RPs) vs. Lower surgical volume was evaluated on 30-day mortality (p=0.049). Higher surgical volume (>27 radical prostatectomies) was associated with significantly lower 30-day mortality compared to lower volume (0.07% vs 0.6%; P=0.049).

synapsesocial.com/papers/6aa6cc884dd50f8a0764cbbahttps://doi.org/10.1111/j.1464-410x.2007.07373.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 130-Day Mortality and Major Complications after Radical Prostatectomy: Influence of Age and Comorbidity2005 · 203 citations
  2. 2Variations in Morbidity after Radical Prostatectomy2002 · 851 citations
  3. 3VARIATIONS AMONG HIGH VOLUME SURGEONS IN THE RATE OF COMPLICATIONS AFTER RADICAL PROSTATECTOMY: FURTHER EVIDENCE THAT TECHNIQUE MATTERS2005 · 200 citations
  4. 4Categorizing a prognostic variable: review of methods, code for easy implementation and applications to decision-making about cancer treatments2000 · 359 citations
  5. 5Comparison of Recommendations by Urologists and Radiation Oncologists for Treatment of Clinically Localized Prostate Cancer2000 · 412 citations