Key result
Targeting a systolic blood pressure <130 mm Hg versus 130-149 mm Hg yielded a non-significant 19% reduction in stroke events in patients with recent subcortical lacunar stroke.
Why the study?
Does a systolic blood pressure target <130 mm Hg reduce stroke in patients with recent subcortical lacunar stroke compared to a target of 130 to 149 mm Hg?
Does a systolic blood pressure target <130 mm Hg reduce stroke in patients with recent subcortical lacunar stroke compared to a target of 130 to 149 mm Hg?
Effect estimate: 19% reduction
p-value: p=not significant
This editorial discusses the SPS3 trial, suggesting that despite a non-significant 19% reduction in stroke, targeting a systolic BP <130 mm Hg is likely beneficial for patients with recent lacunar stroke.
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Ernesto L. Schiffrin (2014) conducted a letter in recent but not acute subcortical lacunar stroke (n=3,020). Systolic blood pressure target <130 mm Hg vs. Systolic blood pressure target 130 to 149 mm Hg was evaluated on stroke (19% reduction, p=not significant). Targeting a systolic blood pressure <130 mm Hg versus 130-149 mm Hg yielded a non-significant 19% reduction in stroke events in patients with recent subcortical lacunar stroke.
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