Key result
Death in hospitalized COVID-19 linked to a ~4-fold higher rate of malignant cardiac arrhythmias versus survivors.
Why the study?
Little is known about malignant cardiac arrhythmias in patients with COVID-19, including their frequency, underlying mechanisms, and impact on mortality.
Cohort (n=140)
No
Absolute Event Rate: 17% vs 4%
p-value: p=0.01
Malignant cardiac arrhythmias occur more frequently in hospitalized COVID-19 patients who die compared to those who survive, though they represent a minority of cardiovascular deaths and are often associated with severe metabolic derangement.
No takes yet. Share an insight, caveat, or question.
Malignant arrhythmias associated with mortality in hospitalized COVID-19; hypothesis-generating and should not yet change practice.
Turagam et al. (2020) conducted a cohort in COVID-19 (n=140). Death (non-survival) vs. Discharge (survival) was evaluated on Composite of cardiac arrest from ventricular tachycardia/fibrillation or bradyarrhythmias such as atrioventricular block (p=0.01). Hospitalized COVID-19 patients who died experienced a significantly higher rate of malignant cardiac arrhythmias compared to those who survived to discharge (17% vs 4%, P=0.01).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: