Key result
Clinical trials consistently show that every 1% reduction in total serum cholesterol level via diet or drugs yields a 2% reduction in the incidence of coronary heart disease.
Population
American women at risk for cardiovascular disease
Design
Review
Authors
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Cholesterol lowering may reduce CHD incidence in women; leaves open need for sex-specific trial confirmation.
Cardiovascular disease is a leading cause of death in women, and lowering total serum cholesterol significantly reduces the incidence of coronary heart disease.
William P. Castelli (1988) conducted a review in Cardiovascular disease. Diet or drugs to lower serum cholesterol was evaluated. Clinical trials consistently show that every 1% reduction in total serum cholesterol level via diet or drugs yields a 2% reduction in the incidence of coronary heart disease.
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