What does this research mean for the field?

Left ventricular ejection fraction ≤ 45%, left main disease, elevated serum creatinine, and multiple CAD risk factors independently increase mortality risk among patients waiting for elective coronary artery bypass graft surgery. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 2022World Journal of Cardiovascular DiseasesOpen Access

Risk Factors for Mortality of Patients Waiting for Elective Coronary Artery Bypass Graft Surgery

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Coronary Artery Disease (n=162). Intervention: Left ventricular ejection fraction ≤ 45% vs. Left ventricular ejection fraction > 45%. Primary outcome: Mortality while waiting for CABG surgery (OR 4.75, 95% CI 1.76-12.78, p=0.002).

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Key result

LVEF ≤45% is linked to ~375% higher mortality risk while awaiting elective CABG.

OR 4.75
95% CI 1.76-12.78
P=0.002
n=162

Population

162 patients waiting for elective CABG in dr. Kariadi General Hospital

Comparison

Patients who died vs survived while waiting for elective CABG

Design

Retrospective cohort study

Follow-up

Mean waiting time 9.8 months

Authors

APAdymas PerdanaDiponegoro University MNMochamad Arif NugrohoDiponegoro University SSSuhartono SuhartonoDiponegoro University

Discussion

Member takes

Implication

LVEF ≤45% flags higher elective CABG waitlist mortality; leaves open whether expedited surgery or bridging strategies improve outcomes.

Study Design

Type

Cohort (n=162)

Multicenter

Structured PICO

Population

162 adults aged 18 to 80 years with coronary artery disease waiting for elective coronary artery bypass graft surgery for more than 3 months, followed for a mean of 9.8 months.

Outcome

Mortality of any cause while waiting for CABGhard clinical

Main Result

Odds Ratio: 4.75 (95% CI 1.76–12.78)

Absolute Event Rate: 40.7% vs 7.8%

p-value: p=0.002

Patients waiting for elective CABG face a high mortality rate (19.7% over a mean 9.8 months), particularly those with reduced LVEF, left main disease, elevated creatinine, or multiple CAD risk factors.

Limitations

Retrospective secondary data dependent on accuracy and completeness of medical records
Absence of surgical priority on the patient waiting list and subjective surgical decisions
Some data on causes of death obtained from family interviews may not describe exact cause

Cite This Study

Perdana et al. (2022) conducted a cohort in Coronary Artery Disease (n=162). Left ventricular ejection fraction ≤ 45% vs. Left ventricular ejection fraction > 45% was evaluated on Mortality while waiting for CABG surgery (OR 4.75, 95% CI 1.76-12.78, p=0.002). Left ventricular ejection fraction ≤ 45% was independently associated with a significantly increased risk of mortality (OR 4.75) in patients waiting for elective coronary artery bypass graft surgery.

synapsesocial.com/papers/6aa6d7164c67234624eed1cd https://doi.org/10.4236/wjcd.2022.126030

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Risk Factors for Mortality of Patients Waiting for Elective Coronary Artery Bypass Graft Surgery

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Risk Factors for Mortality of Patients Waiting for Elective Coronary Artery Bypass Graft Surgery

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

Also Consider