Key result
Hamster brown fat develops from immature cells in a unilocular matrix unlike white fat.
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Distinguishes rodent fat lineages; leaves open applicability to human brown adipose tissue in cardiometabolic disease.
Sites occupied by multilocular brown fat in the adult hamster are occupied by unilocular cells in very young animals. Immature brown fat cells are laid down in the unilocular cell matrix at 3 to 5 days of age. White fat in the hamster does not develop from cells closely resembling mature brown fat.
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Smalley et al. (1967) studied this question. Brown fat in hamsters develops from immature cells laid down in a unilocular matrix at 3 to 5 days of age, while white fat does not develop from cells resembling mature brown fat.
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