Infusions of 2.5-7.8 µg. noradrenaline/Kg./min. over 30 min. and intraperitoneal injections of noradrenaline and adrenaline up to 2000 µg/Kg, in the cat had no effect on the catechol amine content of the heart, spleen, liver, kidney and skeletal muscle, except for a slight increase in the adrenaline content. It is concluded that these organs lack the ability to accumulate circulating catechol amines administered in physiologic dosage.
No takes yet. Share an insight, caveat, or question.
U. S. von Euler (1956) studied this question.