Key result
Autologous pericardial mitral valve reconstruction resolves severe infective endocarditis and regurgitation following emergency cesarean.
Case Report (n=1)
Timely emergency cesarean section followed by mitral valve reconstruction using autologous pericardium can successfully manage severe infective endocarditis with heart failure in pregnant patients.
Hypothesis-generating for peripartum valve intervention timing in severe endocarditis; leaves open generalizability without prospective data.
BACKGROUND: A 34-year-old woman at 25 gestational weeks presented with severe respiratory distress secondary to heart failure caused by severe mitral regurgitation and infective endocarditis. CASE PRESENTATION: Transthoracic echocardiography revealed a large (17 mm) vegetation attached to the posteromedial commissure of the mitral valve leaflet. Owing to pulmonary edema and circulatory failure, she underwent emergency cesarean section to improve maternal hemodynamics. Postoperatively, her pulmonary edema resolved, and the hemodynamic status was stable. Thus, mitral valve surgery was scheduled 2 days later. Intraoperative findings confirmed that the posteromedial site of the mitral valve was severely damaged by vegetation and chordae tendineae rupture. The damaged mitral valve leaflet was resected, with seamless reconstruction using a glutaraldehyde-fixed autologous pericardium. Postoperative echocardiogram revealed no residual mitral regurgitation. Despite premature birth, the infant survived but required surgery for patent ductus arteriosus. CONCLUSIONS: This case highlights that through timely intervention and advanced surgical techniques, a patient with severe infective endocarditis, despite being pregnant, can be successfully managed.
No takes yet. Share an insight, caveat, or question.
Anai et al. (2025) conducted a case report in Severe infective endocarditis and mitral regurgitation (n=1). Mitral valve reconstruction using autologous pericardium was evaluated on Resolution of mitral regurgitation and maternal/fetal survival. Mitral valve reconstruction using autologous pericardium following emergency cesarean section successfully treated severe infective endocarditis and mitral regurgitation in a pregnant patient.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: