Key result
Endovascular and hybrid cardiosurgical interventions during pregnancy performed by a multidisciplinary team resulted in zero maternal mortality and only one programmed fetal loss.
Why the study?
The authors sought to share the experience of endovascular interventions in pregnant women and women in labor gained by a national obstetric cardiology team.
Does endovascular cardiosurgical intervention improve outcomes and maintain safety in pregnant women with critically severe heart pathology?
Observational (n=145)
Yes
Does endovascular cardiosurgical intervention improve outcomes and maintain safety in pregnant women with critically severe heart pathology?
Endovascular cardiosurgical interventions can be safely performed in pregnant women with severe heart pathology by a multidisciplinary team, with no maternal mortality observed in this cohort.
Answers are grounded in this paper and cite their sources.
Experience with endovascular interventions in pregnant women with critical cardiac disease is hypothesis-generating; prospective trials needed before wider adoption.
Objective. To share the experience of endovascular interventions in pregnant women and women in labor, gained by national team “obstetric cardiology”. Materials and methods. The algorithm of medical support was presented, including the cases of cardiosurgical interventions performance , for pregnant women with critically severe pathology of the heart, which was based on actual recommendations and own experience. Into the clinic of Amosov National Institute of Cardiovascular Surgery during 6.5 yrs (12.2013 - 05.2020) 145 women-patients were admitted to hospital, in 79 of them cardiosurgical intervention was done. Endovascular cardiosurgical operations were performed in 36 patients, and the hybrid - in 2. Urgent and emergency endovascular interventions were performed in 17 women-patients with various terms of pregnancy (15 - 35 weeks) and in 2 women in labor. Conditionally-elective cardiosurgical interventions were performed in 17 women-patients on various terms of pregnancy (as a rule, in II trimester) and in 2 women in labor. In 34 patients the interventions were performed with fetus in utero. Early and late maternal mortality was absent. One «programmed» loss of the fetus have occurred on 12-th week of pregnancy with the inborn heart failure. Modern views on impact of ionized radiation and contrast substances on fetus were presented, and the methods of lowering of their potential harm. Conclusion. There was trusted, that while applying strict indications for performance of endovascular interventions during pregnancy, these methods of diagnosis and treatment are more secure in comparison with «open» operative interventions and may be performed under supervision of experienced multidisciplinary team, taking into account the pregnancy term and the fetus defense.
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Сіромаха et al. (2020) conducted an observational in Critically severe heart pathology during pregnancy (n=145). Endovascular and hybrid cardiosurgical interventions vs. Conservative management was evaluated on Maternal mortality and fetal loss. Endovascular and hybrid cardiosurgical interventions during pregnancy performed by a multidisciplinary team resulted in zero maternal mortality and only one programmed fetal loss.
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