Key result
Patients with non-erosive reflux disease were significantly less likely to have an abnormal pH test (45%) compared to those with erosive oesophagitis (75%) or Barrett's oesophagus (93%) (P=0.0001).
Population
149 consecutive patients seen for classic heartburn symptoms, including 71 with non-erosive reflux disease…
Design
Cross-sectional
Authors
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May support selective pH testing in NERD; leaves open prospective validation of clinical utility.
Cross-Sectional (n=149)
Absolute Event Rate: 45% vs 75%
p-value: p=0.0001
Patients with non-erosive reflux disease represent a heterogeneous group that commonly demonstrates a negative pH test and lower acid reflux events compared to erosive oesophagitis and Barrett's oesophagus.
Martinez et al. (2003) conducted a cross-sectional in Non-erosive reflux disease (NERD) (n=149). Non-erosive reflux disease (NERD) vs. Erosive oesophagitis and Barrett's oesophagus was evaluated on Abnormal pH test (p=0.0001). Patients with non-erosive reflux disease were significantly less likely to have an abnormal pH test (45%) compared to those with erosive oesophagitis (75%) or Barrett's oesophagus (93%) (P=0.0001).
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