Key result
ST depression in leads V1 and V2 is linked to higher mid-posterior RWMA incidence.
Why the study?
Does ST deviation in precordial leads correlate with regional wall motion abnormalities on echocardiography in patients with first inferior acute myocardial infarction?
Cross-Sectional (n=109)
Does ST deviation in precordial leads correlate with regional wall motion abnormalities on echocardiography in patients with first inferior acute myocardial infarction?
p-value: p=<0.02
Specific ST segment deviations in precordial leads correlate significantly with regional wall motion abnormalities and right ventricular involvement in patients with first inferior acute myocardial infarction.
May flag mid-posterior involvement on ECG in inferior MI; hypothesis-generating and requires prospective validation before clinical use.
We assessed the correlation between ST deviation in each of the six precordial leads and the presence of regional wall motion abnormalities (RWMA) as assessed by transthoracic echocardiography in 109 patients with first inferior acute myocardial infarction. ST depression in lead V1 and V2 was associated with higher incidence of RWMA of the mid-posterior segment (p < 0.02 for both leads). The specificity of ST segment depression in leads V1 and V2 for RWMA in mid-posterior segment was 87 and 57%, and the sensitivity 36 and 70%, respectively. Patients with ST depression in leads V2 or V3 had worse global RWMA score than patients without ST depression in these leads (p = 0.009 and p = 0.025, respectively). Patients with an ST elevation in lead V1, but not in leads V2 or V3, had a higher prevalence of right ventricular involvement (p < 0.0001). ST elevation in lead V5 was associated with more frequent involvement of the apical portion of the inferior wall (p < 0.02), with specificity of 88% and sensitivity of 33%. Global RWMA score was significantly worse for patients with ST elevation than for patients with isoelectric ST in lead V5 (p = 0.024). ST elevation in lead V6 was associated with RWMA in the mid-posterior segment (p < 0.006), with specificity of 91% and sensitivity of 33%, and worse global RWMA score (p = 0.022).
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Golovchiner et al. (2002) conducted a cross-sectional in first inferior acute myocardial infarction (n=109). ST deviation in precordial leads vs. absence of ST deviation was evaluated on regional wall motion abnormalities (RWMA) of the mid-posterior segment (p=<0.02). ST depression in leads V1 and V2 was associated with a higher incidence of regional wall motion abnormalities of the mid-posterior segment (p < 0.02 for both leads).
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