The forebrain, brain stem, and spinal cord contribution to the control of locomotion is reviewed in this chapter. The lamprey is used as an experimental model because it allows a detailed cellular analysis of the neuronal network underlying locomotion. The focus is on cellular mechanisms that are important for the pattern generation, as well as different types of pre- and postsynaptic modulation. Neuropeptides target different cellular and synaptic mechanisms and cause long-lasting changes (> 24 h) in network function.
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Grillner et al. (1998) studied this question.
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