Key result
Cardiac disease linked to ~120% greater risk of severe outcomes in severe maternal morbidity.
Why the study?
Does the presence of cardiac disease increase the risk of severe maternal morbidity and mortality in pregnant women with severe complications?
Cross-Sectional (n=8,243)
Yes
Does the presence of cardiac disease increase the risk of severe maternal morbidity and mortality in pregnant women with severe complications?
Heart disease in pregnant women is significantly associated with a higher occurrence of severe maternal outcomes, including maternal near miss and maternal death.
Answers are grounded in this paper and cite their sources.
Cardiac disease signals higher risk in severe maternal morbidity; leaves open whether targeted interventions improve near-miss or mortality rates.
BACKGROUND: To evaluate maternal heart disease as a cause or complicating factor for severe morbidity in the setting of the Brazilian Network for Surveillance of Severe Maternal Morbidity. METHODS AND FINDINGS: Secondary data analysis of this multicenter cross-sectional study was implemented in 27 referral obstetric units in Brazil. From July 2009 to June 2010, a prospective surveillance was conducted among all delivery hospitalizations to identify cases of severe maternal morbidity (SMM), including Potentially Life-Threatening Conditions (PLTC) and Maternal Near Miss (MNM), using the new criteria established by the WHO. The variables studied included: sociodemographic characteristics, clinical and obstetric history of the women; perinatal outcome and the occurrence of maternal outcomes (PLTC, MNM, MD) between groups of cardiac and non-cardiac patients. Only heart conditions with hemodynamic impact characterizing severity of maternal morbidity were considered. 9555 women were included in the Network with severe pregnancy-related complications: 770 maternal near miss cases and 140 maternal death cases. A total of 293 (3.6%) cases were related to heart disease and the condition was known before pregnancy in 82.6% of cases. Maternal near miss occurred in 15% of cardiac disease patients (most due to clinical-surgical causes, p<0.001) and 7.7% of non-cardiac patients (hemorrhagic and hypertensive causes, p<0.001). Maternal death occurred in 4.8% of cardiac patients and in 1.2% of non-cardiac patients, respectively. CONCLUSIONS: In this study, heart disease was significantly associated with a higher occurrence of severe maternal outcomes, including maternal death and maternal near miss, among women presenting with any severe maternal morbidity.
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Campanharo et al. (2015) conducted a cross-sectional in Severe maternal morbidity (n=8,243). Cardiac disease during pregnancy vs. Non-cardiac patients with severe maternal morbidity was evaluated on Severe Maternal Outcome (Maternal Near Miss or Maternal Death) (PR 2.2, 95% CI 1.7-2.8). Among women with severe maternal morbidity, the presence of cardiac disease was associated with a 2.2-fold increased risk of severe maternal outcomes (maternal near miss and maternal death).
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