Wear particles of acrylic cement, similar to other biomaterials, can cause periprosthetic osteolysis and formation of extraosseous cement granuloma (ECG). Expansive granuloma can manifest as a tumorous mass adjacent to the knee prosthesis, or it even can damage the popliteal artery and lead to false aneurysm formation. Suspicion of these two conditions requires a complex diagnostic approach and eventually revision of the endoprosthesis itself or reparation of the popliteal artery. Despite the beneficial fixative properties of acrylic cement (methylene-polymethacrylate), which are important for implantation of joint prostheses, the acrylic cement can also cause severe complications related to the wear process.
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Ireneusz Babiak (2014) studied this question.
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