Key result
A recently published trial suggests that amlodipine plus either hydrochlorothiazide or perindopril is a more effective combination therapy for treating hypertension in black Africans.
Why the study?
Does amlodipine plus either hydrochlorothiazide or perindopril improve blood pressure control in black Africans with hypertension?
Does amlodipine plus either hydrochlorothiazide or perindopril improve blood pressure control in black Africans with hypertension?
Amlodipine combined with either hydrochlorothiazide or perindopril is highlighted as an effective combination therapy for hypertension in black Africans.
Although different combination therapies are currently used for treating hypertension among blacks, the authors of a recently published trial suggest amlodipine plus either hydrochlorothiazide or perindopril is a more effective combination. Calcium channel blockers are usually recommended as first-line treatment for control of hypertension.1 Among blacks, one or more antihypertensive medications are added to calcium channel blockers when sole treatment is inadequate for blood pressure control. However, there is uncertainty about which drug combination is more effective for use as combination therapy. In the UK for instance, the National Institute for Health and Care Excellence recommends use of either an ACE inhibitor, an angiotensin receptor blocker (ARB), or a …
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Igho Onakpoya (2019) conducted an editorial in Hypertension. Amlodipine plus either hydrochlorothiazide or perindopril was evaluated. A recently published trial suggests that amlodipine plus either hydrochlorothiazide or perindopril is a more effective combination therapy for treating hypertension in black Africans.
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