Key result
Rheumatic heart disease accounts for ~76% of cardiac disease in pregnancy, linked to maternal heart failure.
Observational (n=229)
No
In a Saudi Arabian cohort from 1982-1998, rheumatic heart disease was the most common cardiac complication of pregnancy, and heart failure occurred in a notable subset of patients despite mostly low baseline NYHA class.
The outcome of 274 viable pregnancies in 229 patients with cardiac disease that delivered at the King Fahad Hospital, Al-Khobar, Saudi Arabia, between 1982 and 1998 was reviewed. The incidence was 0.6% of deliveries. Rheumatic heart disease complicated 208 (75.9%) pregnancies, congenital heart lesion in 49 (17.9%) and the remaining 17 (6.2%) pregnancies were a miscellaneous group that included supraventricular tachycardia, ectopic beats, ischaemic heart disease and cardiomyopathies. The NYHA grading was between 1-2 in 243 (88.7%) pregnancies antenatally. Thirty-one patients developed heart failure, most commonly in the antenatal period, 29 of whom were of Grade 1-2. One mother in the series died from heart failure following a cesarean section. She had had a mitral valvotomy before pregnancy and was categorised as Grade 2, antenatally. The perinatal mortality rate was 14.6/1000 deliveries in the study group. Prophylactic antibiotics were given to all the patients an hour before delivery. There were two instances of bacterial endocarditis in the series.
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Md. Shamim Rahman (2000) conducted an observational in Maternal cardiac disease in pregnancy (n=229). Maternal cardiac disease was evaluated on Pregnancy outcomes (heart failure, maternal mortality, perinatal mortality).
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