The subcutaneous implantation of Spirometra mansonoides spargana into hypophysectomized rats produced a striking increase in body weight and tibial cartilage width comparable to that noted with growth hormone. Other tissue responses confirmed this similarity. Injection of plasma from implanted rats also produced a growth hormone-like response including a stimulation of the uptake of 35SO42- by costal cartilage.
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Steelman et al. (1970) studied this question.