Key result
Resting radial artery L-FMC weakly correlates with carotid IMT whereas FMD does not.
Why the study?
Is there a correlation between peripheral endothelial function measures and carotid intima-media thickness in patients undergoing coronary angiography?
Population
513 consecutive patients undergoing diagnostic coronary angiography
Design
Cross-sectional
Authors
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L-FMC weakly associates with carotid IMT unlike FMD; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=513)
Is there a correlation between peripheral endothelial function measures and carotid intima-media thickness in patients undergoing coronary angiography?
p-value: p=0.008
Resting endothelial function (L-FMC) correlates weakly with subclinical carotid atherosclerosis (IMT), but this relationship is much weaker than the correlation with age.
Schaefer et al. (2012) conducted a cross-sectional in Patients undergoing diagnostic coronary angiography (n=513). Peripheral endothelial function measures (L-FMC and FMD) was evaluated on Correlation with carotid intima-media thickness (IMT) (p=0.008). Resting radial artery flow-mediated constriction (L-FMC) showed a weak correlation with carotid intima-media thickness (p=0.008), whereas flow-mediated dilation (FMD) did not (p=0.13).
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