Key result
MRI of 5 children with congenital hemiplegia suggests silent in utero infarction drives some cases.
Case Report (n=5)
MRI findings suggest that some cases of congenital hemiplegia in term neonates may be due to clinically silent periventricular venous infarction that occurred in utero.
May warrant considering silent in utero periventricular venous infarction in term congenital hemiplegia; leaves open confirmation in larger prospective cohorts.
MRI in five term children with congenital hemiplegia without clinically apparent prenatal or perinatal difficulties showed a focal or porencephalic enlargement of the lateral ventricle and periventricular T2 prolongation, which were identical to findings of periventricular venous infarction seen in preterm children. Some cases of congenital hemiplegia in term neonates may be due to clinically silent periventricular venous infarction that occurred in utero.
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Takanashi et al. (2003) conducted a case report in Congenital hemiplegia (n=5). MRI was evaluated on MRI findings. MRI in 5 term children with congenital hemiplegia showed findings identical to periventricular venous infarction, suggesting some cases may be due to clinically silent in utero infarction.
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