What question did this study set out to answer?

To describe the neuroimaging characteristics and long-term neurodevelopmental outcomes of middle cerebral artery territory infarctions in preterm and full-term infants.

April 1, 1997Neuropediatrics

Infarcts in the Vascular Distribution of the Middle Cerebral Artery in Preterm and Fullterm Infants

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Authors

LVLinda de VriesNetherlands Institute for Neuroscience FGFloris GroenendaalUtrecht University PEP. EkenWilhelmina Children's Hospital

Discussion

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Implication

Case series reveals branch-specific clinical outcomes following middle cerebral artery infarcts in neonates, indicating that main branch occlusion uniformly leads to hemiplegia.

Key Points

To describe the neuroimaging characteristics and long-term neurodevelopmental outcomes of middle cerebral artery territory infarctions in preterm and full-term infants.
Evaluated 23 preterm and full-term infants diagnosed with middle cerebral artery infarctions using cranial ultrasound.
Confirmed diagnoses via postmortem examination in 2 infants and magnetic resonance imaging (MRI) during the neonatal period or infancy in 18 of 20 survivors.
Categorized cases by anatomical vascular distribution into main branch occlusion (n=7) versus cortical or lenticulostriate branch involvement (n=16) and tracked clinical outcomes.
Main branch involvement (n=7, with 3 infants <35 weeks gestational age) was detected on postnatal day 1 or 2, and 100% of survivors developed hemiplegia, with 2 also developing epilepsy.
Branch or lenticulostriate involvement (n=16, with 13 infants ≤34 weeks gestational age) appeared between day 4 and day 24 postnatally, resulting in cerebral palsy in 3 infants and global delay in 3 infants.

Cite This Study

Vries et al. (1997) studied this question.

synapsesocial.com/papers/6a9caea83c308413cc57aaac https://doi.org/10.1055/s-2007-973679

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Implication

Case series reveals branch-specific clinical outcomes following middle cerebral artery infarcts in neonates, indicating that main branch occlusion uniformly leads to hemiplegia.

Infarcts in the Vascular Distribution of the Middle Cerebral Artery in Preterm and Fullterm Infants

Discussion

Member takes

Implication

Key Points

Cite This Study

Infarcts in the Vascular Distribution of the Middle Cerebral Artery in Preterm and Fullterm Infants

Discussion

Member takes

Implication

Key Points

Cite This Study

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