Impact of Educational Intervention on Anticoagulation Control Using SAMe-TT22R2 Score-Guided Strategy in Atrial Fibrillation

Background: score was formulated to identify the likelihood of achieving optimal time in therapeutic range (TTR). Objectives: score-guided strategy for an educational-behavioral intervention, compared with usual care on patient's anticoagulation control. Methods: score-guided strategy group, scores 0 to 2 received usual care, >2 received educational-behavioral intervention plus usual care. All received warfarin targeting international normalized ratio 2.0 to 3.0. Primary outcome was TTR at 12 months. Secondary outcomes included TTR at 6 months, thromboembolic and bleeding events, major adverse cardiovascular events at 12 months, and change in AF knowledge at 6 and 12 months. Results: score-guided strategy vs 40.2 [95% CI: 35.9-44.4] with usual care, and the difference between the 2 groups was 0.7 [95% CI: -5.2 to 6.6]). There were no significant differences in secondary outcomes. Conclusions: score guided strategy in anticoagulant-naive Thai patients with atrial fibrillation; TCTR20180711003).