Key result
New stochastic biophysical computer simulation models capillary network growth for comparison with chicken egg data.
A stochastic biophysical computer simulation can model embryonic angiogenesis and generate arterial trees with properties comparable to biological data.
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Simulation matches chick embryo capillary networks; extends biophysical modeling but leaves open human vascular translation.
Sandau et al. (1994) studied Embryonic angiogenesis. Computer simulation of capillary network growth vs. Biological data from the chorioallantoic membrane (CAM) of incubated chicken eggs was evaluated on Dimension of border, time course of growth, and blood pressure. A computer simulation of capillary network growth based on a stochastic process and biophysical principles was developed and compared with biological data from incubated chicken eggs.
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