Key result
Left transcarotid TAVI appears safe after ipsilateral carotid endarterectomy with 0% mortality and no major complications.
Observational (n=9)
TAVI via a left transcarotid approach is feasible and safe in patients with a history of ipsilateral carotid endarterectomy, demonstrating no 30-day mortality or major complications in a small case series.
Supports transcarotid TAVI exploration in this subgroup; hypothesis-generating and requires larger prospective validation.
OBJECTIVES: To assess the feasibility and safety of transcatheter aortic valve implantation (TAVI) through a left transcarotid approach in patients previously operated on for ipsilateral carotid endarterectomy (CEA). BACKGROUND: The healthcare impact of extracranial carotid artery disease is essential as stroke is the third-leading cause of death in industrialized nations and CEA is often present in the history of patients awaiting TAVI. METHODS: The primary endpoint was to evaluate 30-day mortality and freedom from major TAVI-related complications in an observational analysis. RESULTS: From December 2011 to February 2014, we performed 9 TAVI. The mean age was 84.6 years. The procedure was performed without any technical complication or vascular injury in every patient. There was neither intraoperative mortality nor intraoperative major complications. One (11.1%) patient experienced spatial-temporal disorientation but cerebral computed tomography did not show any sign of stroke. Two (22.2%) patients needed the implantation of a pacemaker due to third-degree atrioventricular block appearance. Three (33.3%) patients were transfused with packed red blood cells and 1 (11.1%) patient developed a groin hematoma. Only 1 (11.1%) patient showed a residual paravalvular regurgitation ≥ 2. At 30-day follow-up there was neither mortality nor other TAVI-related complications and echocardiography parameters remained stable. CONCLUSIONS: TAVI through a left transcarotid approach in patients previously operated on for ipsilateral CEA is feasible and safe. The presence of a previous ipsilateral CEA represents no more a limitation to the utilization of this promising access route. At short-term follow-up, mortality and major complications rates are low.
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Pozzi et al. (2014) conducted an observational in Aortic valve disease with previous ipsilateral carotid endarterectomy (n=9). Transcatheter aortic valve implantation (TAVI) through a left transcarotid approach was evaluated on 30-day mortality and freedom from major TAVI-related complications. TAVI through a left transcarotid approach in patients with previous ipsilateral carotid endarterectomy was feasible and safe, with 0% mortality and no major TAVI-related complications at 30 days.
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