What is the clinical evidence from this study?

Study design: Cohort. Population: Aortic valve disease requiring primary isolated AVR (n=124). Intervention: Primary isolated open aortic valve replacement. Primary outcome: Hospital mortality.

What does this research mean for the field?

Primary isolated open aortic valve replacement in octogenarians achieves an observed hospital mortality of 5.6% with favorable 5- and 10-year actuarial survival rates of 88% and 50%, respectively. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

March 21, 2010European Journal of Cardio-Thoracic SurgeryOpen Access

Primary isolated aortic valve surgery in octogenarians

View Full Paper

Ask AI

Bookmark

Key result

Isolated open AVR in octogenarians shows ~6% hospital mortality and strong long-term survival.

n=124

Population

124 consecutive octogenarians undergoing primary isolated open aortic valve replacement. Excluded combined…

Design

Cohort

Follow-up

mean 77 months

Authors

EFEnrico FerrariInterventional / Structural Cardiology PTPiergiorgio TozziUniversity Hospital of Lausanne MHMichel HurniUniversity of Lausanne

Discussion

Member takes

Implication

AVR yields low observed mortality and favorable survival in octogenarians; leaves open generalizability and comparison with contemporary TAVR.

Study Design

Type

Cohort (n=124)

Structured PICO

Population

124 consecutive octogenarians (mean age 82, 63% female) undergoing primary isolated open aortic valve replacement, followed for a mean of 77 months.

Exposure

Primary isolated open aortic valve replacement (AVR)

Outcome

Hospital mortality, early neurological events, and long-term survivalhard clinical

Primary isolated open aortic valve replacement in octogenarians is associated with acceptable hospital mortality and satisfactory long-term survival.

Cite This Study

Ferrari et al. (2010) conducted a cohort in Aortic valve disease requiring primary isolated AVR (n=124). Primary isolated open aortic valve replacement was evaluated on Hospital mortality. Primary isolated open aortic valve replacement in octogenarians resulted in an observed hospital mortality of 5.6% and actuarial survival estimates of 88% at 5 years and 50% at 10 years.

synapsesocial.com/papers/6aa76266ba4e028df6353ed2 https://doi.org/10.1016/j.ejcts.2010.01.049

View Full Paper

Ask AI

Bookmark

Implication

AVR yields low observed mortality and favorable survival in octogenarians; leaves open generalizability and comparison with contemporary TAVR.

Primary isolated aortic valve surgery in octogenarians

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Primary isolated aortic valve surgery in octogenarians

Discussion

Member takes

Implication

Study Design

Structured PICO

Cite This Study

Also Consider

Also Consider