Strategies for overcoming cancer research challenges for early-career investigators in sub-Saharan Africa: a narrative review

Cancer is a leading cause of morbidity and mortality globally, disproportionately affecting low and middle-income countries (LMICs). High-quality research is an essential component of national cancer control programs. However, inequitable distribution of investigator opportunities and resources perpetuates a growing disparity in cancer care. This is particularly true for SSA researchers early in their careers. This review discusses the challenges and solutions to research capacity building in SSA and draws on evidence from the literature and regional experience to describe practical solutions across ten domains that shape early-career development in cancer research: training opportunities, research agendas, time management, funding, logistics, institutional research support, mentorship, ethical and cultural considerations, collaboration, and research subject participation. Actionable strategies are outlined for institutions, governments, and international partners to strengthen research capacity and support early-career investigators (ECIs) in advancing locally relevant cancer research in SSA.