Sixteen patients with advanced Hodgkin's disease were treated with intensive combination chemotherapy (MOPP). Fourteen achieved complete remission. Many had been previously treated with radiation therapy or chemotherapy or both. Toxic effects were minimal and easily controlled. MOPP therapy represents the chemotherapeutic treatment of choice for patients with advanced Hodgkin's disease, and can be safely administered to outpatients, utilizing community medical facilities.
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Lowell H. Greenberg (1972) studied this question.
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