Key result
Blood pressure is the principal factor linked to reactive hyperemia index variability in healthy adolescents.
Observational
Blood pressure is the primary independent contributor to variability in the reactive hyperemia index in healthy adolescents, highlighting the need to account for age and maturational changes when interpreting this marker.
Reactive hyperemia index is a measure of endothelial function used to assess subclinical atherosclerosis. When evaluated in healthy adolescents, significant changes in endothelial function were correlated with advancing age, pubertal status, and blood pressure. Blood pressure was the principal contributor to reactive hyperemia index variability independent of age, lipid profile, body mass index, and/or pubertal status. Interpretation of this peripheral vascular marker should include age and maturational changes in paediatric patients.
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Deda et al. (2014) conducted an observational in Healthy adolescents. Blood pressure was evaluated on Reactive hyperemia index variability. Blood pressure was the principal contributor to reactive hyperemia index variability in healthy adolescents, independent of age, lipid profile, body mass index, and pubertal status.
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