Key result
Unilateral adrenalectomy achieves sustained disease control without recurrence or adrenal insufficiency in two PPNAD cases.
Why the study?
Does unilateral adrenalectomy provide sustainable disease control in patients with primary pigmented nodular adrenal disease?
Population
2 twin female patients with primary pigmented nodular adrenal disease and a known pathogenic PRKA1A mutation…
Design
Case_report
Follow-up
3 years for patient A, 18 months for patient B
Authors
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Unilateral adrenalectomy may achieve sustainable control in select PPNAD; leaves open optimal patient selection and need for larger studies.
Case Report (n=2)
Does unilateral adrenalectomy provide sustainable disease control in patients with primary pigmented nodular adrenal disease?
Unilateral adrenalectomy can be a successful therapeutic approach for patients with mild PPNAD, avoiding the risk of subsequent adrenal insufficiency.
Kyrilli et al. (2018) conducted a case report in Primary pigmented nodular adrenal disease (PPNAD) (n=2). Unilateral adrenalectomy was evaluated on Disease control without recurrence and adrenal insufficiency. Unilateral adrenalectomy provided sustained disease control without recurrence or adrenal insufficiency at 18 months and 3 years in two twin female patients with PPNAD.
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