Key result
Carney complex is linked to severe hypertension and hypercortisolism during pregnancy.
Case Report (n=1)
Carney complex should be considered as a rare cause of hypercortisolism and severe hypertension during pregnancy.
Alerts clinicians to monitor for severe hypertension in Carney complex pregnancies; leaves open optimal management strategies.
BACKGROUND: Carney complex is a rare, autosomal-dominant, multisystem disorder characterized by endocrine overactivity, spotty skin pigmentation, and myxomas. CASE: We present the case of a 24-year-old primigravid woman with a pregnancy complicated by Carney complex. At 18 weeks of gestation, severe hypertension developed. Medical history was significant for chronic hypertension, nephrolithiasis, and an atrial myxoma excised in 2011. She had Cushingoid features, an elevated 24-hour urine free cortisol, and a cutaneous myxoma. At 26 weeks of gestation, superimposed preeclampsia developed. She underwent a primary classical cesarean delivery, delivering a live female weighing 650 g. CONCLUSION: Carney complex is a rare cause of hypercortisolism and hypertension during pregnancy. It should be considered when features of Cushing syndrome and severe hypertension are present.
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Spaniol et al. (2014) conducted a case report in Carney complex in pregnancy (n=1). Carney complex was evaluated. Carney complex is a rare cause of hypercortisolism and severe hypertension during pregnancy, as demonstrated in a 24-year-old woman who developed superimposed preeclampsia at 26 weeks of gestation.
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